ACNE TREATMENT WITH BEE VENOM POWDER

Acne – is one of the most common types of skin disorders. It happens when the tiny hair follicles get blocked with dead skin and lead to the production of sebum. And that, as a result, leads to pimples and breakouts called acne.

Inhibitory Effects of Bee Venom on Propionibacterium Acnes-Induced Inflammatory Skin Disease in an Animal Model Introduction
​P. acnes (propionibacterium acnes), a type of skin acne, is one of the main contributing factors for the inflammatory module of acne. Prescription medicines meant for treating acne make use of a combination of different treatments. They include strong antibiotics that lead to side effects apart from their few positive antibacterial effects. Most commonly these medicines cause suppression of the host inflammatory responses. 

Method: BV (purified bee venom) contains Apis mellifera, which is an integral part of the modern treatment regimes. It has also been used in traditional medicines to cure different illnesses and diseases. This study was conducted, with two different groups, to examine the therapeutic effect of bee venom against the p. acnes. First of all, the mice, of both groups were injected p. acnes intradermally to induce inflammatory skin disease in them. Later, only one group was administered bee venom to carry out a comparison.

After inducing the subject model mice with p. acne, bee venom was applied right at the same location where p. acne was given.  According to histological observation, it was found that p. acne induction in the right ear leads to a visible increase in the population of infiltrated inflammatory cells. But after the treatment of bee venom, this specific reaction was controlled in the p. acne induced mice when compared with those mice, which were not given bee venom.

Expression levels of interleukin (IL) - 1β and tumor necrosis factor (TNF) α, were remarkably induced in bee venom treated mice when compared with those who were not treated. Furthermore, bee venom treatment tremendously prevented CD14 and TLR2 expression in the p. acne injected tissue. The binding activity of AP1 (activator protein) and NFκB (nuclear factor kβ) was also brought down after bee venom treatment.

Result 
According to this study, which made use of an animal model, it can be said that bee venom delivers an inhibitory effect on the inflammatory diseases. Data obtained from this clinical study also indicates that bee venom can be used as a potent anti-acne agent in different cosmetics and pharmaceutical products. 

Source: ​Inhibitory effects of bee venom on Propionibacterium acnes-induced inflammatory skin disease in an animal model
Further reading:
​Complementary therapies for acne vulgaris
Effects of cosmetics containing purified honeybee (Apis mellifera L.) venom on acne vulgaris​​