STUDIES & CLINICAL TRIALS OF BEE VENOM

Bee venom therapy is used to treat immune-related diseases, for example, arthritis. New research data shows that bee venom has protective immune responses against a wide range of conditions, including asthma, Parkinson's disease, and more. We have gathered the latest research in bee venom treatment here.​​

Below are the topics for several studies. Several studies overlap each other by looking into further studies and discussing previous findings. Let us know if you would like to read more about research for a specific disease or condition where bee venom can help, and we can look into it for you.

​The primary use of bee venom is in cosmetic skincare products.
So let's start with the most important studies covering that area.

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Skin
​The beneficial effects of honeybee-venom serum on facial wrinkles in humans
Bee venom ameliorates compound 48/80-induced atopic dermatitis-related symptoms
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Wound treatment
Biological effects of treatment of an animal skin wound with honeybee venom
Cell regeneration and wound treatment. (Effects of bee venom on keratinocyte migration
​Wound healing: time to look for intelligent, ‘natural’ immunological approaches?
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​How safe is bee venom in topical applications?
​Acute Dermal Toxicity Study of Bee Venom (Apis mellifera L.) in Rats
Bee venom processes human skin lipids for presentation by CD1a
Skin Sensitization Study of Bee Venom (Apis mellifera L.) in Guinea Pigs
Myorelaxant Effect of Bee Venom Topical Skin Application in Patients with RDC/TMD 
Emulsion-Based Intradermal Delivery of Melittin in Rats
Evaluation of Phototoxic and Skin Sensitization Potentials of PLA2-Free Bee Venom​​

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​TOPICS WITH DEDICATED pages that explains the studies in more detail

• Acne
• ​Allergy
• Alopecia areata
• ALS
• Alzheimers
• ​Arthritis
• Asthma
• Atopic Dermatitis (Eczema)
• Baculovirus
• Cancer & Tumors (General Page​​)
• Diabetes
• Bacteria
• Bocavirus - see Parvovirus
• Breast Cancer
• Cervical Cancer
• Corona Virus - Covid19 - SARS-CoV-2
• Fungal Infections
• ​HIV​​
• Inflammation
• Lateral Epicondylitis (Tennis Elbow)
• Liver Injury 
• ​​Lung Inflammation & Respiratory Inflammation​
• Lyme Disease
• Lymphedema
• Multiple Sclerosis
• Microbes
• ​Neuropathic & Neurologic Pain​
• Obesity
• Osteoarthritis​
• ​Ovarian Cancer
• Parvovirus & Bocavirus
• ​​Parkinson
• Psoriasis
• Skin Derma - See Skin-section above and Acne, Atopic Dermatitis (Eczema), Psoriasis and Wrinkles 
• Systemic Sclerosis
• ​Rheumatoid Arthritis
• Wilting Disorder
• ​Wrinkles

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Unsorted studies WITHOUT DEDICATED page (YET)

With links directly to the scientific data
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​Ankylosing Spondylitis
Bee venom has been shown to treat Ankylosing Spondylitis (Zaitsev & Poriadin)

Benign prostatic hyperplasia
Bee venom suppresses testosterone-induced benign prostatic hyperplasia by regulating the inflammatory response and apoptosis

​Bursitis/Tendinitis (Pain in shoulder, wrist, biceps, leg, knee (patellar), ankle, hip, etc.) 
Therapeutic application of anti-arthritis, pain-releasing of bee venom and its constituent compounds

​​CDC -Chagas Disease
Melittin peptide kills Trypanosoma cruzi parasites by inducing different cell death pathways.

Central Nervous System 
The Effects of Bee Venom Acupuncture on the Central Nervous System and Muscle in an Animal hSOD1G93A Mutant
Integrative Korean medicine as a possible conservative treatment for mild cervical spondylotic myelopathy: One-year follow-up case report (CARE-compliant)

Cold Allodynia
Effect of Bee Venom Acupuncture on Oxaliplatin-Induced Cold Allodynia in Rats
Serotonergic mechanism of the relieving effect of bee venom acupuncture on oxaliplatin-induced neuropathic cold allodynia in rats

​Colon Cancer
Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B
Order test kit for Colon Cancer here

Fibrosis
The Protective Effect of Bee Venom on Fibrosis Causing Inflammatory Diseases

Liver fibrosis
Melittin attenuates liver injury in thioacetamide-treated mice through modulating inflammation and fibrogenesis
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Muscoskeletal
​Inspection and Electronic Medical Records

Neurodegenerative Diseases
Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders
Animal Toxins as Therapeutic Tools

Post-Herpetic Neuralgia
Bee stings, a remedy for postherpetic neuralgia? A case report.

Renal fibrosis
The Protective Effect of Melittin on Renal Fibrosis in an Animal Model of Unilateral Ureteral Obstruction 

Rheumatic Fever
Curative Properties of Honey and Bee Venom

Sexual dysfunction
Sweet Bee Venom Pharmacopuncture May be Effective for Treating Sexual Dysfunction 

Schistosoma
​Effect of bee venom on Schistosoma 

Sclerosis
Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models 

Spinal cord
Injury Model 

Synovial Fibroblast
Immunomodulatory Effects of Bee Venom in Human Synovial Fibroblast Cell Line ​​